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Test Code ECUMP Eculizumab Monitoring Panel, Serum

Useful For

Therapeutic drug monitoring of eculizumab

Profile Information

Test ID Reporting Name Available Separately Always Performed
C5FX C5 Complement, Functional, S Yes Yes
C5AG2 C5 Complement, Antigen, S Yes, (Order C5AG) Yes
INT86 ECUMP Interpretation No Yes

Method Name

C5AG2: Nephelometry

C5FX: Automated Liposome Lysis Assay

Reporting Name

Eculizumab Monitoring Panel, S

Specimen Type

Serum Red


Specimen Required


Patient Preparation:

1. Fasting preferred

2. Recommended timeframe for the blood draw is a trough, or immediately prior to next intravenous infusion.

Specimen Type: Serum

Collection Container/Tube: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1.5 mL

Collection Instructions:

1. Immediately after drawing the specimen, place the tube on wet ice.

2. Spin down and separate serum from clot.

3. Freeze specimen within 30 minutes.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Frozen 14 days

Reference Values

C5 COMPLEMENT ANTIGEN

10.6-26.3 mg/dL

 

C5 COMPLEMENT FUNCTIONAL

29-53 U/mL

Day(s) and Time(s) Performed

Varies

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

See Individual Test IDs

CPT Code Information

86160-Complement; antigen, each component

86161-Complement; functional activity, each component

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ECUMP Eculizumab Monitoring Panel, S In Process

 

Result ID Test Result Name Result LOINC Value
C5FX C5 Complement, Functional, S 60472-8
C5AG2 C5 Complement, Antigen, S In Process
INT86 ECUMP Interpretation In Process