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Test Code XMDSOP Opiate Confirmation, Meconium

Additional Codes

XMDSOP (MWHC)

OPATM (MAYO)

Reporting Name

Opiate Confirmation, M

Useful For

Detection of maternal prenatal opiate/opioid use up to 5 months before birth

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Meconium


Specimen Required


Chain of custody is recommended for this test. Chain-of-Custody Meconium Kit (T653) is available upon request.

 

Container/Tube: Stool container (T288)

Specimen Volume: 1 g (approximately 1 teaspoon)

Collection Instructions: Collect entire random meconium specimen.

Additional Information:

1. For chain-of-custody information, see Chain-of-Custody Meconium Kit (T653).

2. Specimen that arrives with a broken seal does not meet the chain-of-custody requirements.

3. The laboratory recommends sending chain-of-custody specimens by overnight shipment.


Specimen Minimum Volume

0.3 g (approximately 1/4 teaspoon)

Specimen Stability Information

Specimen Type Temperature Time
Meconium Frozen (preferred) 28 days
  Refrigerated  28 days
  Ambient  14 days

Reference Values

Negative

Positives are reported with a quantitative LC-MS/MS result.

Cutoff concentrations

Codeine by LC-MS/MS: 50 ng/g

Hydrocodone by LC-MS/MS: 50 ng/g

Hydromorphone by LC-MS/MS: 50 ng/g

Morphine by LC-MS/MS: 50 ng/g

Oxycodone by LC-MS/MS: 50 ng/g

Oxymorphone by LC-MS/MS: 50 ng/g

Day(s) and Time(s) Performed

Monday through Friday, Sunday; Varies

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

80361

80365

G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
OPATM Opiate Confirmation, M 69026-3

 

Result ID Test Result Name Result LOINC Value
31848 Morphine 69027-1
31850 Oxymorphone 69028-9
31849 Hydromorphone 68541-2
31847 Codeine 68542-0
31852 Oxycodone 68543-8
31851 Hydrocodone 68544-6
31868 Interpretation 69050-3
31869 Chain of Custody No LOINC Needed

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)