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Test Code XPEPS Electrophoresis, Protein, Serum

Additional Codes

XPEPS (MWHC)

PEL (MAYO)

Reporting Name

Electrophoresis, Protein, S

Useful For

Monitoring patients with monoclonal gammopathies

 

Diagnosis of monoclonal gammopathies, when used in conjunction with immunofixation

 

Protein electrophoresis alone is not considered an adequate screen for monoclonal gammopathies

Profile Information

Test ID Reporting Name Available Separately Always Performed
TPE Total Protein Yes, (order TP) Yes
ELP Protein Electrophoresis No Yes

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
IMFX Immunofixation No No

Testing Algorithm

If a discrete electrophoresis band is identified, the laboratory will evaluate the serum protein electrophoresis and, if necessary, perform immunofixation at an additional charge.

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Serum

Specimen Required

Patient Preparation: Fasting (12 hour) preferred but not required

Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 1 mL

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Ambient  14 days
  Frozen  14 days

Reference Values

PROTEIN, TOTAL

≥1 year: 6.3-7.9 g/dL

Reference values have not been established for patients that are <12 months of age.

 

PROTEIN ELECTROPHORESIS

Albumin: 3.4-4.7 g/dL

Alpha-1-globulin: 0.1-0.3 g/dL

Alpha-2-globulin: 0.6-1.0 g/dL

Beta-globulin: 0.7-1.2 g/dL

Gamma-globulin: 0.6-1.6 g/dL

An interpretive comment is provided with the report.

Day(s) and Time(s) Performed

Monday through Saturday; Continuously until 2 p.m.

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

84155-Protein, total

84165-Protein, electrophoresis

86334-Immunofixation (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PEL Electrophoresis, Protein, S In Process

 

Result ID Test Result Name Result LOINC Value
TPE Total Protein 2885-2
2769 Albumin 2862-1
2770 Alpha-1 Globulin 2865-4
2771 Alpha-2 Globulin 2868-8
2773 Beta-Globulin 2871-2
2774 Gamma-Globulin 2874-6
2785 A/G Ratio 44429-9
22308 M spike 33358-3
22309 M spike 33358-3
15254 Impression 12851-2

Method Name

TPE: Biuret

ELP: Agarose Gel Electrophoresis

IMFX: Immunofixation and/or Immunodiffusion

Forms

If not ordering electronically, complete, print, and send a General Request Form (T239) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/general-request-form.pdf).

Necessary Information

Indicate if multiple myeloma is suspected.