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Test Code XPROU Electrophoresis, Protein, 24 Hour, Urine

Additional Codes

XPROU (MWHC)

EPU (MAYO)

Reporting Name

Electrophoresis, Protein, U

Useful For

Monitoring patients with monoclonal gammopathies

 

Urine protein electrophoresis alone is not considered an adequate screening for monoclonal gammopathies

Profile Information

Test ID Reporting Name Available Separately Always Performed
PTU Protein, Total, U Yes Yes
PEU Protein Electrophoresis, U No Yes

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
IFXU Immunofixation, U No No

Testing Algorithm

If a discrete electrophoresis band is identified, the laboratory will evaluate the urine protein electrophoresis and, if necessary, perform immunofixation at an additional charge.

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Urine

Specimen Required

Collection Container/Tube: Clean, plastic urine collection container

Submission Container/Tube: Plastic, 60-mL urine bottle

Specimen Volume: 50 mL

Collection Instructions:

1. Collect a 24-hour urine specimen.

2. No preservative.

Additional Information:

1. 24-Hour volume is required.

2. If a serum specimen on the same patient will also be submitted, order PEL / Electrophoresis, Protein, Serum under a separate order.

3. See Urine Preservatives in Special Instructions for multiple collections.

Specimen Minimum Volume

25 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 14 days
  Frozen  5 days
  Ambient  72 hours

Reference Values

PROTEIN, TOTAL

<167 mg/24 hours

Reference values have not been established for patients <18 years of age.

Reference values have not been established for patients >83 years of age.

 

ELECTROPHORESIS, PROTEIN

If protein concentration is abnormal, the following fractions, if present, will be reported as a percent of the protein, total.

Albumin

Alpha-1-globulin

Alpha-2-globulin

Beta-globulin

Gamma-globulin

Reference value applies to 24-hour collection. Specimens collected for periods other than 24 hours will be reported in concentration units.

Day(s) and Time(s) Performed

Protein, total: Monday through Sunday; Continuously

Electrophoresis, protein: Monday through Saturday; 12 p.m.

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

84156-Protein, total

84166-Electrophoresis, protein

86335-Immunofixation (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
EPU Electrophoresis, Protein, U In Process

 

Result ID Test Result Name Result LOINC Value
2776 Albumin 13986-5
TP2 Total Protein 2889-4
TM23 Collection Duration 13362-9
2777 Alpha 1-Globulin 13984-0
2779 Alpha 2-Globulin 13987-3
VL21 Urine Volume 19153-6
CONC1 Concentration 35663-4
2780 Beta-Globulin 13988-1
2781 Gamma-Globulin 13989-9
2833 A/G Ratio 44294-7
21446 M spike 42482-0
22307 M spike 42482-0
21447 Impression 32210-7

Method Name

PTU: Dye Binding (Pyrogallol Red)

PEU: Agarose Gel Electrophoresis

IFXU: Immunofixation

Urine Preservative Collection Options

Note: The addition of preservative or application of temperature controls must occur within 4 hours of completion of the collection.

Ambient

Yes

Refrigerated

Preferred

Frozen

Yes

6N HCl

No

50% Acetic Acid

No

Na2CO3

No

Toluene

Yes

6N HNO3

No

Boric Acid

No

Thymol

Yes