Sign in →

Test Code XTACR Tacrolimus, Blood

Additional Codes

XTACR (MWHC)

TAKRO (MAYO)

Reporting Name

Tacrolimus, B

Useful For

Monitoring whole blood tacrolimus concentration during therapy, particularly in individuals coadministered CYP3A4 substrates, inhibitors, or inducers

 

Adjusting dose to optimize immunosuppression while minimizing toxicity

 

Evaluating patient compliance

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Whole Blood EDTA


Specimen Required


Container/Tube: Lavender top (EDTA)

Specimen Volume: 3 mL

Collection Instructions: 

1. Draw blood immediately before a schedule dose.

2. Do not centrifuge.

3. Send specimen in original tube.

Additional Information: Therapeutic range applies to trough specimens drawn immediately prior to a.m. dose.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Whole Blood EDTA Refrigerated (preferred) 14 days
  Ambient  14 days
  Frozen  14 days

Reference Values

5.0-15.0 ng/mL (Trough)

 

Target steady-state trough concentrations vary depending on the type of transplant, concomitant immunosuppression, clinical/institutional protocols, and time post-transplant. Results should be interpreted in conjunction with this clinical information and any physical signs/symptoms of rejection/toxicity.

Day(s) and Time(s) Performed

Monday through Friday; 3 p.m., Saturday, Sunday; 1 p.m.

CPT Code Information

80197

LOINC Code Information

Test ID Test Order Name Order LOINC Value
TAKRO Tacrolimus, B 74097-7

 

Result ID Test Result Name Result LOINC Value
35145 Tacrolimus, B 77348-1

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

Method Name

High-Performance Liquid Chromatography/Tandem Mass Spectrometry (HPLC-MS/MS)

Forms

If not ordering electronically, complete, print, and send a General Request Form (T239) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/general-request-form.pdf).