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Test Code ITCON Itraconazole, Serum

Reporting Name

Itraconazole, S

Useful For

Verifying systemic absorption of orally administered itraconazole

 

The test is indicated in patients with life-threatening fungal infections and in patients considered at risk for poor absorption or rapid clearance of itraconazole.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum Red


Specimen Required


Collection Container/Tube: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL


Specimen Minimum Volume

0.18 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Refrigerated (preferred) 29 days
  Ambient  29 days
  Frozen  29 days

Reference Values

ITRACONAZOLE (TROUGH)

>0.5 mcg/mL (localized infection)

>1 mcg/mL (systemic infection)

 

HYDROXYITRACONAZOLE

No therapeutic range established; activity and serum concentration are similar to parent drug.

Day(s) and Time(s) Performed

Monday-Friday; 8 a.m.

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

80299

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ITCON Itraconazole, S 10989-2

 

Result ID Test Result Name Result LOINC Value
81247 Itraconazole, S 10989-2
5122 Hydroxyitraconazole 18337-6

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.